Don’t tell your students about membranes and how/why they form – let them discover the spontaneous formation of membranes for themselves using this kit that features the amphipathic structure of phospholipids – with their hydrophilic heads and hydrophobic tails. Your students will explore the chemical structure of a phospholipid and then construct a phospholipid monolayer, a micelle and a bilayer, leading to an understanding of the plasma membrane structure. Additional components of this kit allow students to construct lipid bilayers and consider the role of transport proteins in moving ions and small molecules across membranes.
1-Group | 3-Group |
50 Mini Phospholipids | 150 Mini Phospholipids |
5 Membranes | 15 Membranes |
5 Glucose | 15 Glucose |
1 ATP | 3 ATP |
30 H2O | 90 H2O |
28 Na+ | 84 Na+ |
28 K+ | 84 K+ |
1 Aquaporin | 3 Aquaporin |
1 K+ Leak Channel | 3 K+ Leak Channel |
1 Gated K+ Channel | 3 Gated K+ Channel |
1 GLUT1 Carrier Protein | 3 GLUT1 Carrier Protein |
1 Na+/K+ Pump | 3 Na+/K+ Pump |
6 Plastic Pegs | 18 Plastic Pegs |
Large Phospholipids | Large Phospholipids |
3 Saturated Fatty Acid Tails | 9 Saturated Fatty Acid Tails |
4 Unsaturated Fatty Acid Tails | 12 Unsaturated Fatty Acid Tails |
9 Hydroxyl Groups | 27 Hydroxyl Groups |
9 Hydrogen | 27 Hydrogen |
1 Glycerol Backbone | 3 Glycerol Backbone |
1 Phosphatidylinositol | 3 Phosphatidylinositol |
1 Phosphatidylcholine | 3 Phosphatidylcholine |
1 Phosphatidylserine | 3 Phosphatidylserine |
1 Phosphatidylethanolamine | 3 Phosphatidylethanolamine |
1 Sticker Sheet | 3 Sticker Sheets |
Find information about the contents of your Phospholipid & Membrane Transport Kit© and directions for assembling the pieces so you and your students can start exploring phospholipids and membranes.
This activity guide will help you consider different ways you may use these materials. We encourage you to modify these lessons and activities to meet the learning objectives and needs of your specific students.
Student Handout 1 introduces students to the composition and structure of triglycerides and phospholipids. Students use foam pieces to model triglyceride dehydration synthesis and phospholipid synthesis.
Student Handout 2 guides students through a series of activities using simplified representations of phospholipids to model a phospholipid monolayer, micelle and liposome.
Student Handout 3 familiarizes students with passive and active membrane transport using foam representations of aquaporin, a carrier protein, a gated sodium channel and a sodium-potassium pump.
Students can Build phospholipids and triglycerides, demonstrate hydrophobic and hydrophilic properties, construct a membrane and nswer thought questions.
Explore a variety of videos to enhance your use of the Phospholipid & Membrane Transport Kit and classroom study of phospholipids and cell membranes.
A molecular landscape by David Goodsell, PhD illustrates how lipids are stored in large droplets inside cells.
Connections to: A Framework for K-12 Science Education Practices, Crosscutting Concepts, and Core Ideas